Project Description

Glioblastoma is a grade IV astrocytic tumour and is anaggressive brain tumours mostly affecting adults. Survival rates are poor and in an attempt to further understand the cancer and develop treatment that can better fight the tumour and further increase survival rates, experts aim to understand Glioblastoma biology and different genetic alterations that may have an effect on survival. This essay aims to explore two genetic alterations, MGMT gene methylation and IDH gene mutation and their effect on the overall survival rate of Glioblastoma when given the Stupp protocol as treatment.